Masahiro Motosuke
Tokyo University of Science, Japan
Title: Simple way of optical manipulation of particles/cells in microfluidic systems
Biography
Biography: Masahiro Motosuke
Abstract
Optical manipulation of small objects, e.g., particle and cells, has been widely exploited as a fundamental research tool in biochemical analysis for molecules or cell screening. However, utilization of optical force relying on controlling radiation pressure to the targets basically needs fi ne adjustment of optics so that this technology has not been used in Point-of-Care (POC) diagnostics including advanced Lab-on-a-chip (LOAC) platform that is drastically developing fi elds with the aid of micro/nanofabrication. In out study, possibility of optical manipulation for particles or calls in microfl uidic systems without any optical elements was investigated. Firstly, the use of scattering force was considered. Th is allows us to use low-evergy-density light for manipulation. Th en we exploited microfabricated integrated optics which gently focused iraddiated light to targets in microchannel to promote mobility of the targets. Our approach can expand the use of optical force in simpler way toward highly functionalized POC diagnostics based on LOAC platform.